Inferring Selection Intensity and Allele Age from Multilocus Haplotype Structure
نویسندگان
چکیده
منابع مشابه
Inferring Selection Intensity and Allele Age from Multilocus Haplotype Structure
It is a challenging task to infer selection intensity and allele age from population genetic data. Here we present a method that can efficiently estimate selection intensity and allele age from the multilocus haplotype structure in the vicinity of a segregating mutant under positive selection. We use a structured-coalescent approach to model the effect of directional selection on the gene genea...
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ژورنال
عنوان ژورنال: G3 Genes|Genomes|Genetics
سال: 2013
ISSN: 2160-1836
DOI: 10.1534/g3.113.006197